Taxonomy 3 - A multivariate genetic analysis
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Publications : Biological applications
Articles available on request

Immunogenetics of drug-induced skin blistering disorders. Part II: synthesis.
Bowman C, Delrieu O.
Pharmacogenomics. 2009 May;10(5):779-816. Abstract (PubMed)

Immunogenetics of drug-induced skin blistering disorders. Part I: Perspective.
Bowman C, Delrieu O.
Pharmacogenomics. 2009 Apr;10(4):601-21. Abstract (PubMed)

TNF, LTA, HSPA1L and HLA-DR gene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole.
Alfirevic A, Vilar FJ, Alsbou M, Jawaid A, Thomson W, Ollier WE, Bowman CE, Delrieu O, Park BK, Pirmohamed M.
Pharmacogenomics. 2009 Apr;10(4):531-40. Abstract (PubMed)

Investigation into the multidimensional genetic basis of drug-induced Stevens–Johnson syndrome and toxic epidermal necrolysis. Pirmohamed M, Arbuckle J, Bowman C, Brunner M, Burns D, Delrieu O, Dix L, Twomey J and Stern R.
Pharmacogenomics 2007 Dec; 8(12), 1661–1691. Abstract (PubMed)

Visualizing gene determinants of disease in drug discovery. Delrieu O and Bowman C.
Pharmacogenomics. 2006 Apr;7(3):311-29. Abstract (PubMed)

Publications - Maths and Stats

Whole genome scan algebra and smoothing. Charalambous C, Delrieu O and Bowman C.
In S. Barber, P.D. Baxter, A. Gusnanto & K.V. Mardia (eds) (2008).
The Art and Science of Statistical Bioinformatics, pp.21-27. Leeds, Leeds University Press.
full-text article (pdf) | Clive's presentation (pdf) | LASR 2008 proceedings

On using the correlations of divergences. Delrieu O and Bowman C.
In: Barber, S, Baxter, P D and Mardia, K V (eds) (2007)
Systems Biology and Statistical Bioinformatics. University of Leeds pp 27-35
full-text article (pdf) | Clive's presentation (pdf) | Clive's welcoming presentation (pdf) | LASR 2007 proceedings

Filtering pharmacogenetic signals. Bowman C, Delrieu O and Roger J.
In: S Barber, P D Baxter, K V Mardia and R E Walls (Eds) (2006).
Interdisciplinary Statistics and Bioinformatics. University of Leeds, 41-47
full-text article (pdf) | Clive's presentation (pdf) | LASR 2006 proceedings

Visualisation of gene and pathway determinants of disease. Delrieu O and Bowman C.                     <== LASR 2005 princeps paper
In: S. Barber, P. D. Baxter, K. V. Mardia and R. E. Walls (Eds) (2005).
Quantitative Biology, Shape Analysis, and Wavelets. University of Leeds, 180pp. 21-24
full-text article (pdf) | LASR 2005 proceedings

Posters

Visualisation of gene by gene interactions in pharmacogenetics (poster). Delrieu O and Bowman C.
International Congress Of Human Genetics, Brisbane Australia, 6-11th August 2006
full poster (pdf) | abstract (ICHG 2006)

Filtering pharmacogenetic signals (poster). Bowman C, Delrieu O and Roger J.
International Congress Of Human Genetics, Brisbane Australia, 6-11th August 2006
full poster (pdf) | abstract (ICHG 2006)

Talks

Pharmacogenetics of drug-induced blistering skin reactions. Bowman C and Delrieu O.
Wellcome Trust Sanger Institute, International Pharmacogenomics Conference, Hinxton, Cambridge UK - 20th Oct 2007.
slides (pdf)

Divergences and using their correlations -
Bowman C and Delrieu O.
Department of Mathematics - University of Reading, UK - Oct 2007.
slides (pdf)

Pharmacogenetics of drug-induced blistering skin reactions. Bowman C and Delrieu O.
British Pharmacist Conference - Manchester, UK - Sept 2007.
BPC2007 | slides (pdf)

On using the correlations of divergences. Delrieu O and Bowman C.
Manchester Interdisciplinary Biocentre, University of Manchester - Sept 2007.
dbkgroup.org   | slides (pdf)

On using the correlations of divergences. Bowman C and Delrieu O
University of Newcastle - Sept 2007.
slides (pdf)

Citations

Sequentially testing for a gene–drug interaction in a genomewide analysis.
Patrick Kelly, Yinghui Zhou, John Whitehead, Nigel Stallard, Clive Bowman.
Statistics in Medicine 27:11, 2022-2034 (2008) - Abstract (PubMed)

A single nucleotide polymorphism genotyping method using phosphate-affinity polyacrylamide gel electrophoresis.
Kinoshita E, Kinoshita-Kikuta E, Koike T. (2007). Anal Biochem Feb 15;361(2):294-8. - Abstract (PubMed)

Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism.
Masao Ota, Hirofumi Fukushima, Jerzy K Kulski, Hidetoshi Inoko. (2007). Nature Protocols 2:11, 2857 - Abstract (PubMed)

Sequentially testing for a gene–drug interaction in a genomewide analysis.
Patrick Kelly, Yinghui Zhou, John Whitehead, Nigel Stallard, Clive Bowman. (2007). Statistics in Medicine - Abstract (PubMed)

A tutorial on statistical methods for population association studies.
David J. Balding. (2006). Nature Reviews Genetics 7:10, 781 - Abstract (PubMed)

The 2nd International Drug Hypersensitivity Meeting 18 - 21 April 2006, The University of Liverpool, Liverpool, UK.
Ana Alfirevic, Dean J Naisbitt. (2006). Expert Opinion on Drug Safety 5:5, 729 - Abstract (PubMed)

 

 


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